Hepatitis Vaccines Trials

For the purposes of registration, a clinical trial is any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes.

The first clinical trial of a hepatitis C vaccine in humans has demonstrated safety and unprecedented immune responses, according to research published this week in Science Translational Medicine. B-cells produce antibodies that go after specific invaders. With the hepatitis C virus constantly changing (much like HIV) and having multiple genotypes, it is challenging for scientists to get B-cells to work effectively in a hepatitis C vaccine.

Using “helper” T-cells instead of B-cells that target specific intruders, the new vaccine provokes the immune system to go after the virus with its own defenses. About 15 to 25 percent of people who become infected with hepatitis C clear the virus spontaneously, according to the U.S. Centers for Disease Control and Prevention (CDC). Researchers have known that a powerful T-cell response plays a role in the body’s ability to do so.

The researchers used chimpanzee viruses as vaccine vectors in the trial. “The size and breadth of the immune responses seen in the healthy volunteers are unprecedented in magnitude for a hepatitis C vaccine,” lead researcher Ellie Barnes, of the Nuffield Department of Medicine at Oxford University, said in a press statement.

Hepatitis vaccines 2016 hosting presentations from Global Leaders in the field across the Globe and bringing together vaccine stakeholders including academic researchers, public health clinicians, vaccine policy makers, corporate and vaccine manufacturers. With the generous response and support received from the participants of previous vaccines conferences. OMICS Internationalproudly announces “International Conference on Hepatitis Vaccines” which will be held during June 16–18, 2016 in Rome, Italy. The Theme of the conference is “Innovative research’s & technologies in Hepatitis Vaccines”.

List of Best International Conferences:

  • 3rd World Congress on Hepatitis and Liver Diseases, Oct 17-19, 2016, UAE
  • 2nd International Conference on Hepatology, May 12-14, 2016, USA
  • Annual Conference on Virulent HIV Vaccines, July 28-30, 2016, Thailand
  • 4th International Conference on HIV/AIDS, STDs, & STIs, Oct 3-5, 2016, USA
  • 2nd Hepatitis Cure & Eradication Meeting 2015, Canada
  • 4th Canadian Symposium on Hepatitis C Virus, Canada
  • The Viral Hepatitis Congress, Germany
  • The Singapore Hepatitis Conference, Singapore

  • Animal studies
  • Phase I-IV
  • Post marketing surveillance
  • Subjects- considerations
  • Others

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